Evaluation of the Effect of Transurethral Resection of Bladder Tumors in the Treatment of Bladder Cancer and its Impact on CA19-9 and CA125 Levels

Urology Research

3083-49102981-8230

Bio-Byword Scientific Publishing Pty. Ltd.

10.26689/ur.v1i3.5986

Article

Evaluation of the Effect of Transurethral Resection of Bladder Tumors in the Treatment of Bladder Cancer and its Impact on CA19-9 and CA125 Levelshttps://artdesignp.com/journal/UR/1/3/10.26689/ur.v1i3.5986WangPeigeng

2023

2023-12-30

Objective: To evaluate the impact of transurethral resection of bladder tumors on surgical outcomes and serum tumor markers CA19-9 and CA125 in patients with bladder cancer. Methods: 80 patients with bladder cancer admitted to our hospital were selected and divided into two groups according to different treatment methods, with 40 cases in each group. The control group underwent open resection of bladder tumor, and the observation group adopted transurethral resection of bladder tumors. The two groups’ surgical indicators and levels of serum tumor markers CA19-9 and CA125 before and after treatment were observed and compared. Results: The operation time, bladder irrigation time, and intraoperative bleeding volume of the observation group were less than those of the control group, and the difference was statistically significant (P < 0.05); Before surgery, there was no statistically significant difference in serum CA19-9 and CA125 levels (P > 0.05). After surgery, the serum CA19-9 and CA125 levels of the two groups of patients were significantly lower than those before surgery. Moreover, the serum CA19-9 and CA125 levels in the observation group were significantly lower than those in the control group after surgery (P < 0.05). Conclusion: Transurethral resection of bladder tumors in the treatment of bladder cancer can significantly improve various surgical indicators and reduce the levels of bladder cancer tumor markers CA19-9 and CA125. The surgical effect and prognosis are good and it is worthy of clinical application and promotion.

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